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3-(Trimethylsilyl)propargyl alcohol

CAS No.: 5272-36-6      Formula: C6H12OSi

Weight: 128.24400

Synonyms: 3-TriMethylsilyl-2-propyn-1-ol; 3-trimethylsilylprop-2-yn-1-ol; 3-(Trimethylsilyl)propargyl Alcohol;


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Description

Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

Basic Information
CAS No.:
5272-36-6
Synonyms:
3-TriMethylsilyl-2-propyn-1-ol; 3-trimethylsilylprop-2-yn-1-ol; 3-(Trimethylsilyl)propargyl Alcohol;
Formula:
C6H12OSi
Molecular Weight:
128.24400
PSA:
20.23000
LogP:
0.85950
Properties
Appearance & Character:
Density:
0.865 g/mL at 25 °C(lit.)
Melting Point:
Boiling Point:
76 °C11 mm Hg(lit.)
Flash Point:
152 °F
Storage Conditions:
2-8ºC
Safety Info
Customs Code:
2931900090
WGK Germany:
3
Hazard Category Code:
R36/37/38
Security Instructions:
S23-S24/25
Dangerous Goods Sign:
Xi