1-(3-Sulfopropyl)Pyridinium Hydroxide, Inner Salt
CAS No.: 15471-17-7 Formula: C8H11NO3S
Weight: 201.24300
Synonyms: 1-(3-Sulfopropyl)pyridinium betain; 1-(3-Sulfopropyl)pyridinium Hydroxide Inner Salt; 3-(1-Pyridinio)propanesulfonate; 3-(1-Pyridinio)-1-propanesulfonate; 3-(Pyridin-1-ium-1-yl)propane-1-sulfonate;
A non detergent sulfobetaine used as a mild solubilizing and stabilizing agent for halophilic malate dehydrogenase, halophilic elongation factor Tu (hTu), pig heart malate dehydrogenase, chicken egg white lysozyme and E. coli beta-galactosidase. Preserves the antigenic conformation of serine protease gp76. Does not interfere with colorimetric assays using p-nitrophenylphosphate and o-nitrophenyl-b-D-galactopyranoside as substrates. Reduces aggregation and significantly improves protein renaturation. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Can be easily removed by dialysis.